Clinical manifestations:
Men, more common, male to female ratio of about 2:1,2 / 3 of patients aged 40 to 70 years old. About half of the patients described the history of asbestos exposure. Slow onset health search, variety of clinical manifestations. Epithelial-type and mixed type of pleural mesothelioma, often accompanied by a large number of pleural effusion ù, but usually only a small amount of fiber types with or without pleural effusion. Epithelium of patients seems to be more involving the subclavian or axillary lymph nodes and extend to the pericardium, contralateral pleura, and peritoneum; fiber multi-distant metastasis and bone metastasis.
Early stage of disease, the lack of specific symptoms, 60% ~ 90% of patients with chest pain, shortness of breath, dry cough and shortness of breath , approximately 10.2% of patients have fever and other uncomfortable symptoms, 3.2% of the patients with joint pain mainly v. symptoms of patients often cough, mostly dry cough, no sputum or sputum volume small, there is no sputum blood Patients with malignant pleural mesothelioma, the symptoms of shortness of breath, obviously cupping network, especially since the activities of chest tightness, shortness of breath, increased significantly, with a break to alleviate symptoms of dyspnea secondary to pleural effusion, pleural effusion and tumor extent with the increase of aggravated . Early in the pleural cavity fluid is free, and then gradually restricted parcels, the last large piece of tumor tissue is gradually replaced as a vague dull chest pain initially, when the tumor invasion intercostal nerve pain limitations.
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